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Aldeyra Therapeutics (ALDX) investor relations material

Aldeyra Therapeutics Corporate Presentation summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Corporate Presentation summary16 Dec, 2025

Mission and approach

  • Focus on discovering innovative therapies for immune-mediated diseases by modulating protein systems rather than targeting single proteins, aiming to optimize multiple pathways and minimize toxicity.

Financial position and pipeline

  • Cash, cash equivalents, and marketable securities totaled $75.3M as of 9/30/2025, expected to fund operations into the second half of 2027.

  • Broad immunology pipeline includes reproxalap (ocular), ADX-248 (oral), ADX-246 (intravitreal), and ADX-2191 (intravitreal) for various immune and retinal diseases.

RASP platform and pharmacology

  • RASP (reactive aldehyde species) modulation is a novel, systems-based approach that targets multiple proteins, potentially reducing toxicity and broadening therapeutic activity.

  • RASP are implicated in inflammation, lipid synthesis, and autoimmunity, making them a promising target for diverse diseases.

AbbVie option exercise post-PDUFA strategy
ADX-2191 PVRL treatment duration
Oral RASP modulators' broad applicability
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Frequently asked questions

Aldeyra Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing therapies for immune-mediated diseases. The company is engaged in advancing its pipeline of drug candidates, which target diseases caused by inflammation and tissue damage. Aldeyra's approach is centered on modulating immune responses to treat conditions such as ocular and systemic inflammatory diseases. Its lead therapeutic areas include ophthalmology, with treatments aimed at conditions like dry eye disease and allergic conjunctivitis. The company's goal is to provide new treatment options for diseases with limited or inadequate therapies. The company is headquartered in Lexington, Massachusetts, and its shares are listed on the NASDAQ.

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