Aligos Therapeutics
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Aligos Therapeutics (ALGS) investor relations material

Aligos Therapeutics Q1 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q1 2026 earnings summary7 May, 2026

Executive summary

  • Focused on developing therapeutics for liver diseases and viral infections, with three clinical-stage candidates: pevifoscorvir sodium (HBV), ALG-055009 (MASH/obesity), and ALG-097558 (coronavirus).

  • Pevifoscorvir sodium received FDA Fast Track Designation for chronic HBV infection; Phase 2 B-SUPREME trial ongoing with positive interim analysis and DSMB recommendation to increase sample size.

  • Entered an exclusive license with Amoytop for pevifoscorvir sodium in Greater China, receiving $25M upfront and eligibility for up to $420M in milestones and royalties.

  • ALG-055009 showed positive Phase 2a results in MASH, with significant liver fat reduction and favorable safety profile; funding and out-licensing options under evaluation.

  • IND-enabling studies for ALG-170675 (ASO for HBV) are underway, with development costs in China funded by Amoytop.

Financial highlights

  • Revenue from customers was $2.8M for Q1 2026, up from $0.3M in Q1 2025, driven by a milestone payment from Amoytop.

  • Net loss for Q1 2026 was $23.0M, or $(2.21) per share basic, compared to net income of $43.1M, or $5.12 per share basic, in Q1 2025.

  • Research and development expenses increased 61% year-over-year to $23.4M, mainly due to higher clinical trial costs for pevifoscorvir sodium.

  • General and administrative expenses rose 27% to $6.4M, reflecting higher personnel and legal costs.

  • Cash, cash equivalents, and short-term investments totaled $54.9M as of March 31, 2026.

Outlook and guidance

  • Current cash and expected Amoytop upfront payment are projected to fund operations into Q4 2026.

  • Additional capital will be required to continue operations beyond Q4 2026; management is actively seeking further financing.

  • Topline data from the Phase 2 B-SUPREME study for pevifoscorvir sodium anticipated in 2027, with a second interim analysis for the HBeAg+ cohort expected in H2 2026.

  • Long-term post-treatment data from Phase 1 study to be presented at EASL 2026 Congress.

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