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Aligos Therapeutics (ALGS) investor relations material
Aligos Therapeutics Q1 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Focused on developing therapeutics for liver diseases and viral infections, with three clinical-stage candidates: pevifoscorvir sodium (HBV), ALG-055009 (MASH/obesity), and ALG-097558 (coronavirus).
Pevifoscorvir sodium received FDA Fast Track Designation for chronic HBV infection; Phase 2 B-SUPREME trial ongoing with positive interim analysis and DSMB recommendation to increase sample size.
Entered an exclusive license with Amoytop for pevifoscorvir sodium in Greater China, receiving $25M upfront and eligibility for up to $420M in milestones and royalties.
ALG-055009 showed positive Phase 2a results in MASH, with significant liver fat reduction and favorable safety profile; funding and out-licensing options under evaluation.
IND-enabling studies for ALG-170675 (ASO for HBV) are underway, with development costs in China funded by Amoytop.
Financial highlights
Revenue from customers was $2.8M for Q1 2026, up from $0.3M in Q1 2025, driven by a milestone payment from Amoytop.
Net loss for Q1 2026 was $23.0M, or $(2.21) per share basic, compared to net income of $43.1M, or $5.12 per share basic, in Q1 2025.
Research and development expenses increased 61% year-over-year to $23.4M, mainly due to higher clinical trial costs for pevifoscorvir sodium.
General and administrative expenses rose 27% to $6.4M, reflecting higher personnel and legal costs.
Cash, cash equivalents, and short-term investments totaled $54.9M as of March 31, 2026.
Outlook and guidance
Current cash and expected Amoytop upfront payment are projected to fund operations into Q4 2026.
Additional capital will be required to continue operations beyond Q4 2026; management is actively seeking further financing.
Topline data from the Phase 2 B-SUPREME study for pevifoscorvir sodium anticipated in 2027, with a second interim analysis for the HBeAg+ cohort expected in H2 2026.
Long-term post-treatment data from Phase 1 study to be presented at EASL 2026 Congress.
- Annual meeting to vote on directors, auditor, stock plan amendment, and executive pay proposals.ALGS
Proxy filing29 Apr 2026 - Proxy seeks approval for director elections, auditor, ESPP amendment, and executive pay votes.ALGS
Proxy filing29 Apr 2026 - Pevifoscorvir sodium and ALG-055009 show strong clinical and commercial potential in HBV and MASH.ALGS
Corporate presentation16 Apr 2026 - Pevifoscorvir sodium achieves superior HBV suppression and safety, with strong regulatory support.ALGS
Corporate presentation23 Mar 2026 - Clinical and financial progress achieved, with pivotal HBV data expected in 2027.ALGS
Q4 20255 Mar 2026 - Pevi delivers deep, durable HBV suppression with no resistance, setting a new clinical benchmark.ALGS
Jefferies London Healthcare Conference 20253 Feb 2026 - ALG-055009 achieved up to 46.2% liver fat reduction and favorable safety in MASH trials.ALGS
Study Result20 Jan 2026 - ALG-00184 delivers robust, resistance-free HBV suppression, surpassing current therapies.ALGS
8th Annual MASH Investor Conference19 Jan 2026 - Global phase 2 hepatitis B study launches with best-in-class efficacy and major 2025 catalysts.ALGS
Piper Sandler 36th Annual Healthcare Conference12 Jan 2026
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