Annexin Pharmaceuticals
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Annexin Pharmaceuticals (ANNX) investor relations material

Annexin Pharmaceuticals Q4 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q4 2025 earnings summary5 Feb, 2026

Executive summary

  • Achieved key milestone with first patients dosed in phase 2a study for ANXV in diabetic retinopathy (DR) and retinal vein occlusion (RVO), with initial results deemed favorable and no safety concerns observed.

  • Focused on expanding clinical data in DR and RVO to attract potential licensing partners and support future financing.

  • Cost-saving measures and delayed activities extended cash runway to June 2026.

Financial highlights

  • Net loss for Q4 2025 was -10,515 TSEK, improved from -12,350 TSEK year-over-year; full-year net loss was -36,893 TSEK, improved from -50,252 TSEK.

  • Operating loss for Q4 was -10,746 TSEK (vs. -12,630 TSEK); full-year operating loss was -37,358 TSEK (vs. -50,480 TSEK).

  • Cash flow from operations for the year was -36,925 TSEK (vs. -50,228 TSEK); year-end cash position was 27,395 TSEK (vs. 16,337 TSEK).

  • Equity per share at year-end was 3.77 SEK (vs. 4.29 SEK); EPS for the year was -5.58 SEK (vs. -11.11 SEK).

  • Solid equity ratio of 83% at year-end (vs. 72%).

Outlook and guidance

  • Financing secured through June 2026 following a 50 MSEK rights issue and cost-saving initiatives.

  • Ongoing evaluation of additional financing options to support continued operations and clinical development.

  • No dividend proposed for 2025.

Future funding strategy beyond June 2026
Impact of initial DR/RVO results on study design?
Ophthalmology focus: impact on licensing timeline?
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Frequently asked questions

Annexin Pharmaceuticals AB is a Swedish biotechnology company focused on developing innovative therapies for cardiovascular and inflammatory diseases. Its lead product, ANXV, is a recombinant human protein, Annexin A5, which has the potential to treat conditions related to blood vessel damage and inflammation. The drug is currently undergoing clinical trials, particularly for Retinal Vein Occlusion (RVO), a condition that can lead to vision loss, and shows potential for broader applications, including in oncology. The company is headquartered in Stockholm, Sweden, and its shares are listed on the Stockholm Stock Exchange.

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