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Black Diamond Therapeutics (BDTX) investor relations material
Black Diamond Therapeutics Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Advanced silevertinib clinical program with Phase 2 NSCLC trial showing promising efficacy and safety as of November 2025.
Preparing to initiate a randomized Phase 2 trial in EGFR-altered GBM in Q2 2026.
Focused pipeline after outlicensing BDTX-4933 and restructuring for operational efficiency.
Financial highlights
Ended 2025 with $128.7 million in cash, cash equivalents, and investments, up from $98.6 million at end of 2024.
Net income for 2025 was $22.4 million, compared to a net loss of $69.7 million in 2024.
License revenue of $70 million recognized in 2025.
R&D expenses for 2025 were $33.6 million, down from $51.3 million in 2024.
G&A expenses for 2025 were $16.6 million, down from $27.5 million in 2024.
Outlook and guidance
Cash position expected to fund operations into the second half of 2028.
Updated clinical data for silevertinib in NSCLC and GBM expected in Q2 2026.
- Silevertinib demonstrates robust efficacy in NSCLC and is advancing to pivotal GBM trials.BDTX
TD Cowen 46th Annual Health Care Conference4 Mar 2026 - BDTX-1535 achieved 42% ORR and durable responses in resistant EGFRm NSCLC at 200 mg.BDTX
Study Update20 Jan 2026 - BDTX-1535 shows strong efficacy and safety in NSCLC, with pivotal data expected in 2025.BDTX
Stifel 2024 Healthcare Conference13 Jan 2026 - Phase 2 EGFR inhibitor shows strong efficacy and safety; key 2025 data and regulatory updates ahead.BDTX
Piper Sandler 36th Annual Healthcare Conference11 Jan 2026 - BDTX-1535 shows promise in NSCLC and GBM, with pivotal data and regulatory milestones ahead.BDTX
24th Annual Needham Virtual Healthcare Conference27 Dec 2025 - Lead oral therapy 1535 targets broad NCMs in NSCLC, with pivotal data and FDA update in Q4 2024.BDTX
Stifel 2025 Virtual Targeted Oncology Forum23 Dec 2025 - Shelf registration allows up to $500M in offerings, with $150M at-the-market via Jefferies.BDTX
Registration Filing16 Dec 2025 - Silevertinib’s Phase II data show high response and CNS activity in lung cancer, with pivotal trials ahead.BDTX
Piper Sandler 37th Annual Healthcare Conference7 Dec 2025 - Silevertinib shows strong efficacy and CNS activity in NSCLC and advances to phase II GBM trial.BDTX
Study Update3 Dec 2025
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