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Bristol-Myers Squibb Company (BMY) investor relations material
Bristol-Myers Squibb Company Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Growth Portfolio revenues increased 16% year-over-year in Q4 2025 and 17% for the full year, nearly offsetting a $4B decline in the Legacy Portfolio, with strong contributions from new launches and established brands.
Key products Opdualag, Breyanzi, and Camzyos each exceeded $1B in annual sales; Reblozyl surpassed $2B.
Multiple clinical and regulatory milestones achieved, with several products now exceeding $1B in annual revenue.
Entered 2026 with solid momentum and a robust pipeline, expecting over 10 new medicines and 30+ launch opportunities by 2030.
Revenue mix continues to shift from legacy to growth products, reflecting successful portfolio transition.
Financial highlights
Q4 2025 total revenues were $12.5B; full-year 2025 revenues reached $48.2B, with Growth Portfolio revenue up 16% to $7.4B in Q4 and 17% to $26.4B for the year.
Opdivo Q4 revenue up 7% to nearly $2.7B; Reblozyl up 21%; Breyanzi up 47%; Camzyos up 57%.
Eliquis Q4 revenue grew 6% to nearly $3.5B, with U.S. revenue up 4%.
Non-GAAP gross margin for FY 2025 was 72.6%; Q4 non-GAAP EPS was $1.26, and FY 2025 non-GAAP EPS was $6.15.
Q4 cash flow from operations was $6.3B.
Outlook and guidance
2026 revenue guidance: $46B–$47.5B, reflecting growth portfolio strength and a 12%-16% decline in legacy portfolio revenue.
Eliquis projected to grow 10%-15% in 2026, with a $1.5B–$2B step-down expected in 2027 due to EU patent expirations and generic entry.
Adjusted diluted EPS guidance for 2026: $6.05–$6.35.
Gross margin expected at 69%-70% in 2026; operating expenses to decline to ~$16.3B.
- TimeTickerHeadlineOpen
- 6 FebMGY
Record production, strong free cash flow, and disciplined capital returns defined 2025. - 6 FebQNST
Record Q2 revenue, $50.2M net income, HomeBuddy acquisition, and AI drive growth. - 6 FebOPGN
Shareholders will vote on seven key proposals, including a new equity plan and company name change. - 6 FebCDP
2025 FFO/share up 5.8% with strong leasing; 2026 outlook positive amid record defense spending. - 6 FebVTR
2025 saw double-digit SHOP NOI and FFO growth, a raised dividend, and $2.5B in investments. - 6 FebREG
2025 delivered record NOI and FFO growth, with 2026 guidance projecting further gains. - 6 FebMNTS
All stock issuance proposals passed except the share increase, which was not approved. - 6 FebCPT
2025 beat guidance; 2026 sees lower FFO, Sun Belt focus, and major asset sales with share repurchases. - 6 FebKOG
Record growth, robust backlog, and a NOK 5.70 dividend proposal drive future expansion. - 6 FebTSBK
Net income rose 19.8% to $8.22M, with higher margins, strong capital, and a dividend increase.
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