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Cardiol Therapeutics (CRDL) investor relations material

Cardiol Therapeutics Corporate Presentation summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Corporate Presentation summary3 Dec, 2025

Strategic focus and pipeline

  • Advancing therapies targeting inflammation in the heart, with late-stage programs for recurrent pericarditis, acute myocarditis, and heart failure.

  • Lead candidate CardiolRx™ targets inflammasome activation, offering a non-immune suppressing, potentially disease-modifying therapy.

  • Strong Phase II data in pericarditis (MAVERIC) and myocarditis (ARCHER) support further development.

  • IND-enabling program for CRD-38 in heart failure, targeting a multi-billion-dollar market.

Clinical trial highlights

  • MAVERIC Phase II showed rapid, durable pain reduction and inflammation control in recurrent pericarditis, with 71% recurrence-free during extension.

  • ARCHER Phase II in acute myocarditis demonstrated significant reductions in LV mass and trends toward reduced fibrosis and edema, with safety confirmed.

  • Phase III MAVERIC trial is enrolling high-risk pericarditis patients, aiming for 50% enrollment in H2 2025 and completion in H1 2026.

Market opportunity and differentiation

  • CardiolRx™ addresses large, underserved populations: 38,000 recurrent pericarditis and 46,000 acute myocarditis patients in the U.S.

  • Orphan Drug Designation granted for pericarditis; potential for additional designations in myocarditis.

  • Recurrent pericarditis market expected to exceed $1B by 2028, with CardiolRx™ offering a differentiated, accessible, non-immunosuppressive profile.

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Q4 202527 Mar, 2026
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Frequently asked questions

Cardiol Therapeutics Inc. is a biopharmaceutical company focused on developing anti-inflammatory and anti-fibrotic therapies for cardiovascular diseases. The company specializes in small molecule therapeutics targeting conditions such as acute myocarditis, heart failure, and other inflammatory heart disorders. The company is headquartered in Oakville, Ontario, Canada, and its shares are listed on the NASDAQ and TSX.

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