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Cinclus Pharma (CINPHA) investor relations material
Cinclus Pharma KOL Event summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Introduction and agenda
Event focused on linaprazan glurate, a next-generation PCAB, and its role in addressing unmet needs in GERD, especially severe erosive GERD.
Agenda included a KOL overview of GERD, limitations of current therapies, real-world patient cases, and a commercial landscape discussion.
KOL background and credentials
Dr. Prateek Sharma, Professor of Medicine, is internationally recognized for advancing GI disease management and has over 550 publications in top journals.
He is a frequent speaker at major scientific meetings and has contributed to clinical guidelines and textbooks.
Market insights and analysis
GERD affects about 20% of the U.S. population and 14% globally, with significant impact on quality of life and work productivity.
Erosive GERD, especially grades C and D, is associated with higher risks of complications like Barrett's esophagus and esophageal cancer.
The severe erosive GERD market in the USA and Europe is estimated at 10 million patients, representing a large, dynamic, and chronic market with frequent drug switching.
PCABs are gaining traction globally, with premium pricing and rapid uptake in markets like Japan and the U.S.
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