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Coya Therapeutics (COYA) investor relations material

Coya Therapeutics Evercore ISI 8th Annual HealthCONx Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Evercore ISI 8th Annual HealthCONx Conference summary2 Dec, 2025

Key accomplishments and milestones in 2025

  • Lead asset advanced into a potentially registration-enabling clinical trial.

  • Interim data from an investigator-initiated trial in frontotemporal dementia showed promising results.

  • Preclinical data demonstrated synergistic potential of GLP-1s with proprietary low-dose interleukin-2.

  • Notable publications and external validation, including a Nobel Prize awarded to a scientific advisory board member.

Scientific platform and strategy

  • Focused on neurodegenerative diseases by restoring Treg numbers and function to reduce inflammation.

  • Utilizes a combination biologic approach with low-dose interleukin-2 and CTLA-4 to sustain Treg function.

  • Consistent results across small trials in ALS, FTD, and Alzheimer's, showing disease progression can be slowed.

Clinical development and trial design

  • ALS phase II trial is a randomized, double-blind, placebo-controlled study with 120 patients and a six-month primary endpoint (ALSFRS).

  • Secondary endpoints include neurofilament light and oxidative stress biomarkers, with patient stratification by disease severity.

  • After six months, placebo patients are re-randomized to treatment for an additional year to gather further data.

Dr. Reddy's deal impact on future capital
Strategy for Alzheimer's/Parkinson's funding
GLP-1 + COYA 301: specific Treg impact
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Q4 202518 Mar, 2026
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Frequently asked questions

Coya Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing proprietary therapies that enhance the function of regulatory T cells (Tregs). The company’s therapeutic platforms include Treg-enhancing biologics, Treg-derived exosomes, and autologous Treg cell therapy. These therapies are aimed at treating neurodegenerative, autoimmune, and metabolic diseases. Coya Therapeutics is headquartered in Houston, Texas, and its shares are listed on the NASDAQ.

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