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Curis
Curis (CRIS) investor relations material
Curis Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary6 Nov, 2025
Executive summary
Progress in clinical studies for emavusertib in PCNSL, CLL, and AML, with ongoing enrollment and new data presentations scheduled at major oncology conferences.
Emavusertib granted orphan drug designation by FDA and EMA for PCNSL; protocol for Phase 2 CLL study filed, with first patient dosing expected late Q4 2025 or early Q1 2026.
Recently sold royalty interest in Erivedge and related assets for $2.5 million, extinguishing a significant liability and ending future royalty revenue.
Accumulated deficit reached $1.3 billion as of September 30, 2025, with continued operating losses and substantial doubt about the ability to continue as a going concern.
Completed registered direct offering and private placement, extending cash runway into 2026.
Financial highlights
Net loss for Q3 2025 was $7.7 million ($0.49/share), improved from $10.1 million ($1.70/share) in Q3 2024; net loss for the nine months ended September 30, 2025, was $26.9 million ($2.19/share), down from $33.8 million ($5.77/share) in 2024.
Revenues for Q3 2025 were $3.2 million, up from $2.9 million in Q3 2024, primarily from Erivedge royalties.
R&D expenses for Q3 2025 were $6.4 million, down from $9.7 million in Q3 2024; G&A expenses were $3.7 million, slightly down from $3.8 million.
Cash and cash equivalents stood at $9.1 million as of September 30, 2025, with 12.7 million shares outstanding.
Weighted average shares outstanding increased to 15.7 million in Q3 2025 from 5.9 million in Q3 2024.
Outlook and guidance
Existing cash and equivalents expected to fund operations into Q1 2026; additional capital required to fund operations beyond that period.
Focused on enrolling additional patients for TakeAim Lymphoma to support regulatory submissions.
First patient in CLL Phase 2 study expected to be dosed late Q4 2025 or early Q1 2026, with data anticipated at ASH 2026.
Plans to seek additional funding through equity, collaborations, or strategic transactions, but faces significant difficulty raising capital.
If unable to secure funding, may need to delay or eliminate R&D programs, consider asset sales, or seek bankruptcy protection.
What are the immediate funding plans?
How do AML triplet DLTs impact future dosing?
CLL study: What defines time-limited treatment?
CLL study: What CR rate would be a strong signal?
Strategy for year-end capital raise
When are PCNSL accelerated submissions expected?
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Next Curis earnings date
Q4 202526 Mar, 2026
Curis
Next Curis earnings date
Q4 202526 Mar, 2026
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Frequently asked questions
Curis Inc. is a biotechnology company focused on developing innovative therapies for the treatment of cancer. The company's research and development efforts concentrate on targeting signaling pathways that play a key role in the growth and survival of cancer cells. Curis works on both proprietary drug candidates and in collaboration with strategic partners to advance its oncology-focused pipeline. Its therapeutic approach includes small molecules and immunotherapies aimed at addressing various forms of cancer, with the goal of improving patient outcomes. The company is headquartered in Lexington, Massachusetts, and its shares are listed on the NASDAQ.
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