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Dynavax Technologies (DVAX) investor relations material
Dynavax Technologies Evercore ISI 8th Annual HealthCONx Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Hepatitis B vaccine market strategy and trends
Targeting 60% market share of a $900M+ market by 2030, with current progress tracking well toward this goal.
Retail segment is key, already holding 63% share, with expectations to exceed 75% as more adult vaccinations shift to retail by 2030.
Growth in retail driven by post-pandemic changes: increased patient comfort, expanded pharmacist authority, and retail infrastructure.
Medicare patients (25% of pharmacy market) present further opportunity as reimbursement improves, aiming to capture more of this segment.
Seasonality patterns are evolving, with retail settings leveraging flu season to increase non-flu vaccine uptake.
COVID vaccine acquisition and development outlook
Recent acquisition of an oral COVID vaccine aims for a differentiated product with a novel mucosal delivery mechanism.
Market focus is on high-risk populations, with current COVID vaccine uptake down 15% year-over-year but still a multi-billion-dollar opportunity.
Deal structure allows for data review before major investment, balancing risk and capital deployment.
Advancement to Phase 3 and commercialization depends on efficacy data and regulatory clarity, with financial capacity to support development.
Efficacy trials will focus on symptomatic infection, with supportive endpoints like hospitalization and severity.
Shingles vaccine and global market potential
U.S. market will focus on the aging cohort and those dissatisfied with current options, with ex-U.S. prevalence market remaining large.
Potential for a booster market as age recommendations lower and vaccine efficacy wanes over time.
Commercialization strategy centers on retail pharmacy, leveraging existing infrastructure for synergy.
Flexible on ex-U.S. partnerships but aims to retain U.S. launch control, targeting early 2030s for market entry.
Upcoming Part 2 study will focus on vaccine response rate in 70+ age group, with supportive T cell and antibody data.
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