Eisai (4523) investor relations material

Executive summary

• Q3 FY2025 revenue rose 3.1% year-on-year to JPY 619.9 billion, driven by strong growth in the pharmaceutical business, especially LENVIMA, DAYVIGO, and LEQEMBI, despite a high prior-year base from one-time payments.

• Operating profit declined 1.7% year-on-year to JPY 54.5 billion due to the absence of one-time outlicensing gains and higher SG&A expenses, but organic business profit contribution doubled.

• Profit attributable to owners of the parent fell 8.1% year-on-year to JPY 41.8 billion; basic EPS was JPY 148.31.

• Full-year forecast maintained at JPY 790 billion revenue and JPY 54.5 billion operating profit, with steady progress toward targets.

• Strategic in-licensing of oncology assets (Taletrectinib and Serplulimab) to strengthen the pipeline and maintain the oncology franchise.

Financial highlights

• Gross profit rose 1.6% year-on-year to JPY 480.7 billion; cost of sales ratio increased to 22.5% due to product mix and drug price revisions.

• R&D expenses decreased 8.5% year-on-year to JPY 114.7 billion, with the R&D-to-revenue ratio down to 18.5%.

• SG&A expenses increased 4.7% to JPY 315.7 billion, mainly from investments in LEQEMBI.

• EPS declined 7.4% year-on-year to JPY 148.31.

• Net cash from operating activities was JPY 57.2 billion, up sharply from the prior year.

Outlook and guidance

• Full-year guidance unchanged: JPY 790 billion revenue, JPY 54.5 billion operating profit, and JPY 41.5 billion profit attributable to owners.

• Dividend forecast is unchanged at JPY 160 per share for FY2025.

• Q4 will see active resource allocation to key pipeline programs and structural reform costs in EMEA.

• Revenue contributions from new in-licensed oncology assets expected from FY2028.

• Management highlights risks from currency fluctuations, global economic conditions, and regulatory changes.