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Eli Lilly and Company (LLY) investor relations material
Eli Lilly and Company Citi Annual Global Healthcare Conference 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Citi Annual Global Healthcare Conference 2025 summary2 Dec, 2025
Leadership transition and strategic focus
Recent transition to head of U.S. operations, with ongoing responsibility for global customer capabilities and expansion of digital platforms like LillyDirect.
Emphasis on expanding access and launches in international markets, especially for obesity treatments and self-pay models.
Focus on leveraging learnings from self-pay in both U.S. and international markets.
Commercial priorities and product strategy
Priorities through 2026 include treating obesity as a chronic disease, innovating consumer offerings, and expanding access via partnerships and direct-to-employer models.
Orforglipron and Zepbound positioned to address different patient needs, with orals as entry points and injectables for those seeking higher efficacy.
Anticipated early Q2 launch for Orforglipron, with both oral and injectable incretins expected to see significant market growth as access expands.
Access, pricing, and payer dynamics
Medicare coverage for obesity treatments could begin as early as April 1, 2026, with broad access and low out-of-pocket costs.
Medicaid access expected to improve gradually, with more significant gains likely in 2027.
Direct-to-consumer pricing for Zepbound reduced, aiming to increase self-pay uptake.
Commercial segment faces ongoing pricing pressure; employer opt-in is a key focus for broader access.
Pace of Medicare/Medicaid access ramp-up
Orforglipron's role: entry point or maintenance?
Key non-incretin growth catalysts for 2026?
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Next Eli Lilly and Company earnings date
Q4 20256 Feb, 2026
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Q4 20256 Feb, 2026
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Frequently asked questions
Pharmaceutical Giant
Eli Lilly and Company, often referred to simply as Eli Lilly, is a global pharmaceutical corporation established in 1876. Headquartered in Indianapolis, the company specializes in the research, development, manufacture, and distribution of pharmaceutical products to address a wide range of health conditions. Throughout its history, Eli Lilly has introduced several notable medications and therapies to the market, but today they’re mainly known for their antidepressants and its main revenue driver, insulin. Their portfolio encompasses treatments for diabetes, oncology, neurodegenerative diseases, and other therapeutic areas.
Founded by Colonel Lilly
Colonel Eli Lilly, a Civil War veteran, founded his pharmaceutical venture in a small brick establishment in Indianapolis in 1876, during an era when the industry was riddled with dubious patent medicine sellers. By 1890, his son J.K. Lilly, Sr. took the helm of the expanding company, later joined by his own sons. Their collective leadership ushered in modern production techniques and research practices, revolutionizing the way pharmaceuticals were manufactured. The Lilly family retained private ownership until 1952 before going public. In partnership with University of Toronto scientists, they spearheaded the mass production of insulin in 1923. Their ventures in the mid-20th century included producing crucial antibiotics and 68% of the U.S. supply of the Salk polio vaccine by 1956, contributing significantly to the decline of polio cases in the 1960s.
Diabetes Experts
Eli Lilly manufactures a multitude of drugs, but a large part of their revenue is driven by the diabetes medications Trulicity and Humalog. Eli Lilly has, as previously mentioned, played a key role in the development of various medications for diabetes. Trulicity (dulaglutide) is an injectable medication used to treat type 2 diabetes. It mimics the actions of the body's natural incretin hormone, helping stimulate insulin release in response to increased blood sugar levels, thereby aiding in glycemic control. Humalog is a fast-acting insulin analog designed to help control blood sugar levels in individuals with both type 1 and type 2 diabetes, taken just before or after meals. The company also produces various medications for mental health issues, cancer, oncology, and more.
Global Player
Eli Lilly's presence is global, distributing its portfolio of medications across multiple continents. Their global strategy revolves around creating strong partnerships with distributors, healthcare systems, and local authorities. Eli Lilly is one of the most influential pharmaceutical companies in the world together with names like Pfizer, Novartis, AbbVie, and several others.
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