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Evaxion Biotech (EVAX) investor relations material
Evaxion Biotech Sidoti's Year End Virtual Investor Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Sidoti's Year End Virtual Investor Conference summary11 Dec, 2025
Strategic platform and partnerships
AI-Immunology platform is clinically validated, enabling rapid and accurate vaccine target discovery, with a 24-hour turnaround and 81% hit rate, reducing costs and time significantly.
Multi-partner approach includes a major outlicensing deal with Merck for the EVX-B3 program, providing $7.5M upfront and up to $592M in milestones and royalties.
Merck holds a 15% equity stake, and the company is open to further collaborations with other pharma and biotech firms.
The platform supports multiple modalities (protein, DNA, mRNA, peptides) and is scalable to various disease areas, including cancer, infectious, and autoimmune diseases.
The company has also attracted interest from organizations like the Gates Foundation for target discovery projects.
Pipeline progress and clinical achievements
Lead candidate EVX-01, a personalized cancer vaccine for advanced melanoma, showed a 75% overall response rate and 25% complete remission in phase II, outperforming Keytruda alone.
EVX-04, a novel AML vaccine targeting the dark genome, is advancing toward first-in-human studies and has generated significant industry interest.
Infectious disease pipeline includes vaccines for Staph aureus, gonorrhea, Group A Streptococcus, and CMV, all in preclinical or early clinical stages.
EVX-B2, a gonorrhea vaccine, is under extended evaluation with Merck, with a decision expected in H1 2026.
The company aims to outlicense programs by phase II, focusing internal resources on early-stage development and partnering for later stages.
Financial execution and outlook
Cash runway extended to the second half of 2027 through strategic deals, public offerings, and debt-to-equity conversion with the European Investment Bank at a premium.
Financial strategy execution has improved the balance sheet and leverage, supporting ongoing R&D and business development.
Stock price has increased 110% in the past six months, driven by key milestones and industry validation.
Resource allocation in 2026 will prioritize oncology programs while advancing infectious disease assets to clinical entry and investing in platform enhancements.
No first right of refusal exists for Merck on EVX-01, allowing flexibility for future partnerships.
EVX-01 partnership strategy post-ESMO data
EVX-B2 evaluation extension with Merck implications
AI platform scalability to new disease areas
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Next Evaxion Biotech earnings date
Q4 20255 Mar, 2026
Next Evaxion Biotech earnings date
Q4 20255 Mar, 2026
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Frequently asked questions
Evaxion Biotech utilizes the AI platform, which is designed to reduce the identification of novel epitopes, and to develop neoantigens, vaccines, and antibody-based therapies; pNLS platform that is designed to identify novel protein structures through computational design; and 2D-to-3D structural similarity searching algorithm. It is developing EB023, a peptide based immunotherapy for the treatment of head and neck cancer. Evaxion Biotech A/S was founded in 2008 and is headquartered in Copenhagen, Denmark.
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