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Evommune (EVMN) investor relations material

Evommune Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary11 Dec, 2025

Executive summary

  • Completed IPO in November 2025, raising $172.5 million in gross proceeds, with net proceeds of $160.4 million, strengthening financial position for upcoming milestones.

  • Focused on developing therapies for chronic inflammatory diseases, with lead candidates EVO756 and EVO301 in Phase 2 trials for multiple indications including CSU, AD, and UC.

  • Anticipates three Phase 2 data readouts in 2026 for EVO756 and EVO301 targeting atopic dermatitis and chronic spontaneous urticaria.

  • Pipeline progress includes positive Phase 2 data for EVO756 in chronic inducible urticaria and ongoing expansion into additional indications.

  • Accumulated deficit reached $192.8 million as of September 30, 2025, with continued net losses expected as R&D and operational expenses increase.

Financial highlights

  • License revenue was $13.0 million for the nine months ended September 30, 2025, up from $7.0 million in the prior year period, driven by milestone payments from Maruho.

  • Revenue for Q3 2025 was $10.0 million, compared to zero in Q3 2024, driven by a licensing collaboration.

  • Net loss for the nine months ended September 30, 2025 was $40.6 million, compared to $46.1 million in the same period in 2024.

  • Research and development expenses increased to $53.6 million for the nine months ended September 30, 2025, primarily due to higher clinical trial and discovery research costs.

  • Cash, cash equivalents, and short-term investments totaled $76.1 million as of September 30, 2025, prior to IPO proceeds.

Outlook and guidance

  • Expects top-line Phase 2b data for EVO756 in CSU in the first half of 2026 and in AD in the second half of 2026.

  • Phase 2a data for EVO301 in AD anticipated in the first half of 2026.

  • Current cash, cash equivalents, short-term investments, and IPO proceeds are expected to fund operations into the second half of 2028.

  • Anticipates continued increases in R&D and G&A expenses as clinical programs advance and company scales operations.

  • No product revenue expected for several years; future funding needs will depend on clinical progress and milestone achievements.

Cash runway post-IPO, considering burn rate
EVO756's unique mechanism: competitive edge
Rationale for new EVO756/EVO301 indications
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