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EXACT Therapeutics (EXTX) investor relations material
EXACT Therapeutics Company presentation summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Oncology development and clinical progress
PS101, a proprietary ultrasound-activated prodrug, demonstrated a 4x increase in tumor shrinkage versus standard of care in Phase 1 for liver metastases and showed excellent safety.
Ongoing Phase 2 ENACT trial in first-line locally advanced pancreatic cancer patients in the US and UK reported positive initial safety and early encouraging treatment responses.
Early ENACT data showed ≥85% reduction in CA 19-9 biomarker and up to 46% tumor shrinkage in initial patients, indicating strong clinical benefit potential.
PS101 enables targeted, organ-specific drug delivery through a non-invasive, ultrasound-activated process, enhancing chemotherapy effects.
The addressable patient population for the lead indication is approximately 30,000 annually in the USA and EU5.
Strategic focus and pipeline expansion
Core focus is on winning in locally advanced pancreatic cancer, with the ENACT Phase 2 trial as the top priority.
Preclinical pipeline includes gene therapy (nonviral delivery), CNS cancers, blood-brain barrier applications, and immuno-oncology combinations.
Preclinical studies show PS101 can open the blood-brain barrier and enhance delivery of various drug formulations.
Immuno-oncology applications and glioblastoma models are being explored, with promising preclinical results.
Broad IP coverage supports expansion into multiple therapeutic areas.
Financials, milestones, and outlook
Raised $13M in December 2024, with up to $6M more from warrant exercises expected in February 2026; 75% of this amount is already secured.
Use of proceeds includes securing the ENACT trial through key data points, expanding IP, and supporting non-clinical research.
Major milestones achieved include final Phase 1 results, regulatory approvals, and initial dosing in Phase 2.
Near-term news flow in 2026 includes publication of Phase 1 results, multiple ENACT trial readouts, and preclinical updates.
Partnership with a leading medical equipment company strengthens device and supply chain support.
- TimeTickerHeadlineOpen
- 6 FebHTOO
Resale registration for 71,429 shares via warrant, with proceeds only on exercise; financial risks persist. - 6 FebVSAT
Q3 revenue up 3% to $1.16B, net income $25M, strong cash flow, Ligado boost, satellite focus. - 6 FebWEC
Targets 7–8% EPS growth, $37.5B capex, and coal exit by 2032 amid surging data center demand. - 6 FebBR
Q2 FY26 recurring revenue grew 8% and adjusted EPS guidance was raised to 9-12%. - 6 FebFFWM
Merger vote includes new non-voting stock class with limited conversion and no voting rights. - 6 FebKKR
Charter amendments seek to modernize governance and establish one share, one vote by 2026. - 6 FebARI
Proposed $9B real estate loan portfolio acquisition highlights disciplined, long-term strategy. - 6 FebSMCI
Q2 revenue jumped 123% to $12.7B, with FY26 guidance raised to at least $40B. - 6 FebRJF
Record revenues and assets, higher dividend, and acquisitions despite lower net income. - 6 FebFFIE
Raising capital for global EV and AI expansion, with regulatory and dilution risks highlighted.
Next EXACT Therapeutics earnings date
Next EXACT Therapeutics earnings date
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