Genscript Biotech
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Genscript Biotech (1548) investor relations material

Genscript Biotech H2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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H2 2025 earnings summary15 Mar, 2026

Executive summary

  • Revenue rose 61.4% year-over-year to $959.5 million, with adjusted net profit up 285% to $230.3 million, driven by global expansion, productization, and platform synergy.

  • All business units—Life Science Group, ProBio, and Bestzyme—delivered sustainable growth, with ProBio revenue surging 309.1% year-over-year.

  • Net loss of $532.4 million was recorded, mainly due to a $320.4 million share of loss and $398.1 million impairment on the Legend Group investment.

  • Significant ESG achievements: MSCI AA rating, FTSE4Good inclusion, EcoVadis silver medal, S&P Global Sustainability Yearbook recognition, and net-zero target by 2050.

  • Prior year profit was inflated by a one-time $3.2 billion gain from Legend Group deconsolidation.

Financial highlights

  • Total revenue reached $959.5 million (+61.4% YoY); gross profit more than doubled to $553.2 million (+103.3% YoY).

  • Adjusted net profit was $230.3 million, up from $59.8 million in 2024 (+285% YoY); net loss was $532.4 million.

  • Adjusted gross profit margin at 51.2%, with adjusted operating profit of $95.4 million.

  • ProBio revenue included nearly $280 million from the LaNova license deal.

  • Cash and bank balances plus wealth management products totaled $843.1 million (+14.3% YoY).

Outlook and guidance

  • 2026 revenue growth guidance: Life Science Group 15–18%, ProBio services 25–30%, Bestzyme 10–15%.

  • Adjusted gross margin expected to reach 52% for Life Science Group, with operating profit margin around 19–20%.

  • Focus on high-quality growth, profitability, automation, digitalization, and global expansion.

  • ProBio targets 20–25% fee-for-service revenue growth and aims for positive EBITDA by 2027.

  • Maintains long-term strategic investment in Legend Group, optimistic about its future value.

Legend impairment impact on group liquidity
Revenue scale of in vivo CAR-T CMC orders
Margin impact of 2026 AI-automation targets
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