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Guard Therapeutics Intl (GUARD) investor relations material
Guard Therapeutics Intl Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Negative topline results from the phase 2b POINTER study led to the termination of the RMC-035 clinical program, marking a significant setback and prompting a strategic review, including potential merger or reverse acquisition options.
The company initiated cost-saving measures, scaled down operations, and began winding down all RMC-035-related activities.
After the reporting period, the company joined a European research consortium to evaluate GTX peptides for Alport's disease.
Financial highlights
Net sales for both Q4 and the full year 2025 were 0 KSEK (0 KSEK in 2024).
Net loss for Q4 was -16,330 KSEK (vs. -25,958 KSEK in Q4 2024); full-year net loss was -108,851 KSEK (vs. -96,066 KSEK in 2024).
Earnings per share for the year were -6.04 SEK (-8.62 SEK in 2024).
Cash and cash equivalents at year-end were 49,826 KSEK (54,186 KSEK in 2024).
Operating loss for the year was -107,195 KSEK (-99,905 KSEK in 2024), mainly due to R&D expenses.
Outlook and guidance
The strategic review is ongoing, with a focus on merger or reverse acquisition, expected to conclude in Q1 2026.
Available cash is considered sufficient to fund operations through 2026.
- Negative POINTER study results prompt strategic review and development pause.GUARD
Q3 202513 Nov 2025 - Phase 2b POINTER showed no significant kidney benefit for RMC-035, prompting strategic review.GUARD
Study Result27 Oct 2025 - Phase 2B kidney trial nears results, with strong data and major partnering discussions ongoing.GUARD
DNB Carnegie Småbolagsdag1 Sep 2025 - Phase 2b POINTER study recruitment completed early; positive safety review and SEK 120M raised.GUARD
Q2 202521 Aug 2025 - Phase 2b POINTER study underway; RMC-035 targets $1B+ global market in cardiac surgery.GUARD
Q3 202413 Jun 2025 - Regulatory progress and new funding position Guard Therapeutics for key clinical milestones.GUARD
Q2 202413 Jun 2025 - Q1 saw rapid clinical progress and SEK 120m in new funding, despite a widened loss.GUARD
Q1 20256 Jun 2025 - Net loss widened as R&D ramped up for POINTER; major capital raise planned for 2025 milestones.GUARD
Q4 20245 Jun 2025
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