Immutep
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Immutep (IMM) investor relations material

Immutep Q2 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2026 earnings summary29 Jan, 2026

Executive summary

  • Entered strategic collaboration with Dr. Reddy's for efti commercialization outside North America, Europe, Japan, and Greater China, receiving ~A$30 million upfront and eligibility for up to ~A$528 million in milestones plus royalties.

  • Strong operational progress in TACTI-004 (KEYNOTE-F91) Phase III trial for 1L NSCLC, with futility analysis on track for Q1 CY2026.

  • Positive clinical data across multiple trials, including INSIGHT-003 (NSCLC), EFTISARC-NEO (soft tissue sarcoma), and AIPAC-003 (metastatic breast cancer).

  • IMP761 Phase I trial in autoimmune diseases showed dose-dependent immunosuppressive effects and favorable safety.

  • Received A$4.6 million R&D tax incentive from the French government.

Financial highlights

  • Cash, cash equivalents, and term deposits totaled A$99.1 million as of 31 December 2025; pro-forma balance of A$129.3 million after Dr. Reddy's upfront payment.

  • Net cash used in operating activities for the quarter was A$9.4 million, down from A$19.0 million in Q1 FY26.

  • Cash used in R&D activities was A$9.9 million, compared to A$15.8 million in the previous quarter.

  • Payments to related parties totaled A$474k for the quarter.

  • Cash reach extended well into Q2 CY2027, excluding future milestone payments.

Outlook and guidance

  • Cash position expected to fund operations well into Q2 CY2027.

  • Additional updates on IMP761 Phase I trial anticipated in H1 CY2026.

  • TACTI-004 futility analysis expected in Q1 CY2026; 50% patient enrollment target anticipated soon.

What does the A$30M vendor payment deferral signify?
How does 30mg efti dose impact TACTI-004 trial?
Why is INSIGHT-003's ORR in low PD-L1 significant?
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Frequently asked questions

Immutep Limited is a clinical-stage biotechnology company, recognized for its pioneering work in developing novel immunotherapy for cancer and autoimmune diseases. The company's research and development efforts are centered on Lymphocyte Activation Gene-3 (LAG-3), a crucial cell surface molecule that plays a significant role in regulating the immune system. Immutep's portfolio includes a range of innovative immunotherapies designed to either stimulate or suppress the immune system to combat cancer or autoimmune diseases. The company is headquartered in Sydney, Australia, and its shares are listed on the Nasdaq.

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