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Inhibrx Biosciences (INBX) investor relations material
Inhibrx Biosciences Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Completed sale of INBRX-101 and spin-off, now focused on two clinical programs: ozekibart and INBRX-106.
Pipeline includes ongoing trials in chondrosarcoma, colorectal cancer, and head and neck squamous cell carcinoma.
Financial highlights
Cash and cash equivalents were $124.2 million as of December 31, 2025.
Net loss for Q4 2025 was $32.8 million ($2.11/share), improved from $47.9 million ($3.09/share) in Q4 2024.
Net loss for FY 2025 was $140.1 million ($9.04/share), compared to net income of $1.7 billion ($114.01/share) in FY 2024, which included a one-time gain from the INBRX-101 transaction.
Research and development expenses decreased to $25.3 million in Q4 2025 (from $33.4 million in Q4 2024) and to $113.0 million in FY 2025 (from $203.7 million in FY 2024).
General and administrative expenses dropped to $5.6 million in Q4 2025 (from $16.7 million in Q4 2024) and to $23.3 million in FY 2025 (from $127.9 million in FY 2024).
Other expense was $1.9 million in Q4 2025 versus other income of $2.1 million in Q4 2024; FY 2025 other expense was $5.0 million versus FY 2024 other income of $2.0 billion (driven by the INBRX-101 gain).
Outlook and guidance
Plans to submit BLA for ozekibart in unresectable/metastatic chondrosarcoma to FDA in early Q2 2026.
Progression-free survival data for ozekibart in colorectal cancer expected in Q2 2026; FDA meeting for accelerated approval in Ewing Sarcoma and fourth-line colorectal cancer planned for H2 2026.
Interim ORR data for INBRX-106 in HNSCC with pembrolizumab expected in Q2 2026; PFS data at ESMO 2026 Congress in Q4 2026.
- INBRX-106 and ozekibart show strong clinical promise, targeting major oncology markets.INBX
Investor presentation20 Mar 2026 - Spin-off and asset sale drove $1.7B net income; strong cash, clinical data expected in 12 months.INBX
Q4 202412 Dec 2025 - Net loss of $107.2M, $1.3M revenue, $153.1M cash, and strong clinical progress for ozekibart.INBX
Q3 202524 Nov 2025 - Ozekibart doubled PFS in chondrosarcoma and showed high response rates in CRC and Ewing sarcoma.INBX
Study Result27 Oct 2025 - Q2 2025 net loss was $28.7M, revenue $1.3M, and cash reserves $186.6M.INBX
Q2 202514 Oct 2025
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