KalVista Pharmaceuticals
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KalVista Pharmaceuticals (KALV) investor relations material

KalVista Pharmaceuticals Corporate Presentation summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Corporate Presentation summary9 Jan, 2026

Mission and strategy

  • Focus on developing therapies for rare diseases with high unmet needs, starting with hereditary angioedema (HAE).

  • Strategy includes leveraging global infrastructure to develop, acquire, or in-license additional innovative therapies.

EKTERLY product overview

  • EKTERLY is the first and only oral on-demand therapy for HAE, approved in seven major global markets.

  • Indicated for acute HAE attacks in patients aged 12 and older, with planned expansion to ages 2-11 in 2027.

  • Demonstrates rapid, sustained relief and a strong safety profile.

HAE disease and treatment landscape

  • HAE is a rare, lifelong disease with unpredictable, potentially life-threatening swelling attacks.

  • Injectable on-demand therapies are underutilized, with significant delays in treatment and many attacks going untreated.

  • Prior to EKTERLY, management relied on parenteral treatments and long-term prophylaxis, often with high burden and cost.

Strategy to achieve $1.5B US market for EKTERLY
Future pipeline strategy beyond EKTERLY
Significance of EKTERLY pediatric expansion
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Q4 202613 Feb, 2026
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Q4 202613 Feb, 2026

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Frequently asked questions

KalVista Pharmaceuticals Inc. is a biopharmaceutical company engaged in the discovery, development, and commercialization of small molecule protease inhibitors, which are primarily aimed at treating diseases with significant unmet medical needs. The company focuses on advancing a portfolio of inhibitors targeting the kallikrein-kinin system, a key pathway in the human body related to swelling and inflammation. KalVista's research has produced sebetralstat, an oral treatment for hereditary angioedema (HAE), a rare and potentially life-threatening genetic condition characterized by spontaneous episodes of swelling. Additionally, the company is exploring oral Factor XIIa inhibitors, which are in preclinical development stages, for the prophylactic treatment of HAE, along with potential therapies for thrombosis and inflammation. The company is headquartered in Cambridge, Massachusetts, and its shares are listed on the NASDAQ.

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