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Nanobiotix (NANO) investor relations material
Nanobiotix Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Closed a non-dilutive royalty financing with HealthCare Royalty (HCRx) valued up to $71 million, with $50 million upfront and $21 million expected in one year upon meeting conditions.
Advanced the JNJ-1900 (NBTXR3) global development program, including first Phase 1 data in esophageal cancer and transfer of Phase 3 study sponsorship to Johnson & Johnson in most regions.
Progressed the Curadigm Nanoprimer program with new patent filings, pre-clinical data, and external collaborations.
Financial highlights
€20.4 million in cash and cash equivalents as of September 30, 2025.
$50 million upfront payment from HCRx extends cash runway, with an additional $21 million expected, providing cash visibility into early 2028.
Outlook and guidance
Clinical updates expected in 2026 from ongoing or completed JNJ-1900 (NBTXR3) Phase 1 studies in melanoma, lung cancer, pancreatic cancer, and esophageal cancer.
Final and updated data from multiple studies, including those sponsored by MD Anderson, anticipated in 2026.
- NBTXR3 demonstrates strong efficacy and safety in head and neck cancer, warranting further trials.NANO
Status Update3 Feb 2026 - NBTXR3 plus radiation and anti-PD-1 achieved strong efficacy and safety in R/M HNSCC.NANO
Study Update31 Jan 2026 - Strong clinical progress and J&J partnership drive NBTXR3's path to market and new innovations.NANO
H.C. Wainwright 26th Annual Global Investment Conference 202421 Jan 2026 - NBTXR3 shows strong promise in head and neck cancer, with pivotal Phase III data due in H1 2026.NANO
Guggenheim Inaugural Global Healthcare Innovation Conference15 Jan 2026 - R3's phase III progress and $2.5B J&J deal highlight broad oncology potential.NANO
Stifel 2024 Healthcare Conference13 Jan 2026 - NBTXR3's phase III progress and J&J partnership drive major oncology and platform expansion.NANO
Jefferies London Healthcare Conference 202413 Jan 2026 - Curadigm's Nanoprimer boosts drug delivery by overcoming liver clearance, enabling broader therapeutic impact.NANO
Status Update10 Jan 2026 - NBTXR3 plus radiotherapy improved survival and biomarker response in pancreatic cancer.NANO
Status Update27 Dec 2025 - Clinical progress and financial discipline extend cash runway to mid-2026.NANO
Q4 202426 Dec 2025 - J&J assumes pivotal trial costs, extending cash runway and supporting major clinical milestones ahead.NANO
Status Update26 Dec 2025
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