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NeuroSense Therapeutics (NRSN) investor relations material
NeuroSense Therapeutics Registration Filing summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Company overview and business model
Clinical-stage biotechnology company developing treatments for neurodegenerative diseases, including ALS, Alzheimer's, and Parkinson's.
Lead candidate PrimeC is an extended-release oral combination of ciprofloxacin and celecoxib, targeting ALS pathology via multiple mechanisms.
PrimeC has orphan drug designation from FDA and EMA, and SME status from EMA.
Positive results from Phase 2b PARADIGM trial, with plans for a pivotal Phase 3 study in ALS starting H2 2025.
Pipeline includes additional candidates for Alzheimer's (CogniC) and Parkinson's (StabiliC), following a similar combined-therapy approach.
Financial performance and metrics
As of June 30, 2025, pro forma cash was $4.1 million, with pro forma as adjusted cash of $10.4 million after the offering.
Accumulated deficit as of June 30, 2025, was $41.4 million.
Pro forma as adjusted total capitalization after the offering is $9.2 million.
Audit report includes a going concern warning due to recurring losses and expectation of significant additional losses.
Use of proceeds and capital allocation
Net proceeds will fund clinical development of PrimeC for ALS, preclinical and clinical work for CogniC (AD) and StabiliC (PD), new product candidates, working capital, and general corporate purposes.
Management retains broad discretion over allocation of proceeds.
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Q4 2025 earnings hit $2.9B, with record refining yields and strong portfolio transformation. - ARCC
FY 2025 delivered $2.01 Core EPS, $1.86 net income/share, and a $0.48 Q1 2026 dividend. - HMN
Record core earnings, 12.4% ROE, and 10% EPS growth guidance for 2026. - AFG
Record underwriting profit, strong ROE, and over $700M returned to shareholders in 2025. - OXBR
Tokenized reinsurance contracts on Solana open Florida's market to global investors. - PNDORA
2025 organic growth reached 6%, with EBIT margin at 23.9% and cautious 2026 outlook.
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Next NeuroSense Therapeutics earnings date
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