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NRx Pharmaceuticals (NRXP) investor relations material

NRx Pharmaceuticals Registration Filing summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Registration Filing summary12 Dec, 2025

Company overview and business model

  • Operates as a clinical-stage biopharmaceutical company focused on novel therapeutics for central nervous system disorders, including suicidal depression, chronic pain, PTSD, and schizophrenia.

  • Develops neuroplasticity-enhancing drugs targeting the NMDA receptor, with two lead candidates: NRX-100 (IV ketamine) and NRX-101 (oral D-cycloserine and lurasidone).

  • Majority owner of HOPE Therapeutics, which provides interventional psychiatry care for treatment-resistant depression and PTSD using neuroplastic drugs, TMS, digital therapeutics, and hyperbaric therapy.

Financial performance and metrics

  • Presents only two years of audited financial statements and reduced management discussion due to smaller reporting company status.

  • Most recent audited financials for years ended December 31, 2024 and 2023, with a going concern explanatory paragraph from auditors.

Use of proceeds and capital allocation

  • Net proceeds from securities sales will primarily support working capital and general corporate purposes to drive growth.

  • Management has broad discretion over allocation, and actual expenditures may vary based on operational and market factors.

  • Pending use, proceeds may be invested in short-term, investment-grade securities.

Going concern: How will this offering help?
Fund NRX-100/101 or HOPE Therapeutics development?
Javitt ownership: Impact on shareholder actions?
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Q4 202513 Mar, 2026
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Frequently asked questions

NRx Pharmaceuticals Inc. (NRXP) is a clinical-stage pharmaceutical company focused on developing novel therapeutics for the treatment of central nervous system disorders. The company's portfolio includes ZYESAMI, an investigational drug for COVID-19 related respiratory failure, and oral therapeutics NRX-100 and NRX-101 for the treatment of bipolar depression in patients with acute suicidal behavior/ideation and sub-acute suicidal ideation and behavior. The company is headquartered in Wilmington, Delaware, and its shares are listed on the Nasdaq.

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