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Nykode Therapeutics (NYKD) investor relations material
Nykode Therapeutics Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Focused on three core assets: Abi-suva (lead HPV16-driven cancer immunotherapy), VB10.NEO (individualized neoantigen therapy), and the ASIT/tolerance platform for autoimmune diseases and allergies.
Advanced Abi-suva into a randomized controlled phase II trial (Abili-T/Ability trial) for first-line head and neck cancer, with protocol submitted to UK authorities and EMA submission planned.
Strengthened proprietary position for VB10.NEO with a new US patent for the NeoSELECT platform and presented validating clinical and preclinical data.
Demonstrated long-lasting, multi-compartment immune modulation with the tolerance/ASIT platform, showing efficacy in multiple autoimmune disease models.
Achieved key milestones: protocol submission for Abili-T trial, supply agreement for pembrolizumab, and new U.S. patent for NeoSELECT platform.
Financial highlights
Q3 2025 revenue and other income: USD 0.1 million (NOK 118,000), down from USD 0.7 million (NOK 665,000) in Q3 2024, mainly due to reduced revenue from Genentech and Regeneron.
Operating expenses reduced to USD 6.4 million (NOK 6.4 million) from USD 15.6 million (NOK 15.6 million) year-over-year, reflecting organizational streamlining and lower clinical activity.
Net loss of USD 3.7 million (NOK 3.7 million), improved from USD 9.7 million (NOK 9.7 million) in Q3 2024.
Cash position of USD 63.9 million (NOK 64 million) at quarter-end; equity of USD 99 million with a 94% equity ratio.
Dividend of USD 32.3 million paid in Q2 2025.
Outlook and guidance
Cash runway extends into 2028, potentially 2029 pending a positive tax case outcome.
Interim data from the ongoing C-03/CO3 trial expected in the first half of 2026; first interim data from the Abili-T/Ability trial anticipated in 2027.
Focus on leveraging peer data readouts in the individualized neoantigen therapy field over the next 15 months.
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