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Penumbra (PEN) investor relations material

Penumbra Piper Sandler 37th Annual Healthcare Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Piper Sandler 37th Annual Healthcare Conference summary3 Dec, 2025

Business performance and sales force developments

  • Expanded sales force with over 50 experienced hires to focus on the growing embolization product line, especially the CAVT portfolio.

  • Ruby XL coil launched, showing strong demand and rapid adoption in its first full quarter.

  • Peripheral vascular coil business expected to grow at the same pace as the rest of the company.

  • Sales force for peripheral vascular is stable, with only minor additions expected as business grows.

  • Margins from these products are accretive.

Product innovation and clinical data

  • Ruby XL coil offers faster, more effective filling of large vessels, addressing a gap in innovation.

  • MMA embolization is a new, fast-growing neuro procedure, with significant early success and a potential $1 billion market opportunity.

  • STORM-PE trial demonstrated mechanical thrombectomy with CAVT is superior to anticoagulation, with strong safety and efficacy data.

  • 3.0 product iteration features both hardware and software upgrades, reducing blood loss and procedure time compared to previous versions.

Market adoption and protocol changes

  • Hospitals are actively updating protocols to adopt new mechanical thrombectomy standards based on STORM-PE data.

  • PRISM program launched to accelerate protocol updates and patient referrals.

  • Referring physicians are increasingly adopting new treatment standards even before formal protocol changes.

  • Penetration rates for mechanical thrombectomy expected to rise as randomized control data supports earlier intervention.

How will Penumbra capitalize on the $1B MMA market?
What's the current pace of STORM-PE protocol changes?
How does 3.0 improve PE procedure efficiency?
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Frequently asked questions

Penumbra Inc designs, develops, and markets medical devices for neurovascular and vascular conditions. Its products support treatments for stroke, peripheral embolization, and thrombectomy procedures, serving healthcare providers and hospitals worldwide. Penumbra operates within the healthcare and medical device sectors. The company is headquartered in Alameda, California, and its shares are listed on the NYSE.

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