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Prelude Therapeutics (PRLD) investor relations material

Prelude Therapeutics Registration Filing summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Registration Filing summary10 Dec, 2025

Company overview and business model

  • Precision oncology company focused on developing novel cancer medicines for underserved patients, leveraging expertise in cancer biology, medicinal chemistry, and clinical development.

  • Pipeline includes kinase inhibitors, targeted protein degraders, and degrader antibody conjugates, with several programs in clinical and preclinical stages.

  • Collaborates with AbCellera Biologics on early-stage discovery programs targeting tumor-specific antigens.

  • Incorporated in Delaware in 2016, with principal offices in Wilmington, Delaware.

Financial performance and metrics

  • In November 2025, received $25 million from Incyte for 6,250,000 shares of non-voting common stock at $4.00 per share.

  • Received an additional $35 million upfront payment from Incyte for an exclusive option on a JAK2V617F inhibitor program.

  • Potential future payments from Incyte could reach up to $910 million, including milestones and royalties, if the option is exercised.

Use of proceeds and capital allocation

  • Will not receive proceeds from the resale of shares by the selling stockholder; all proceeds go to the selling stockholder.

  • Company bears registration and related offering expenses, while the selling stockholder pays commissions and legal fees related to their sales.

Prelude's potential cash from Incyte's JAK2 option?
Incyte's non-voting stock conversion limit impact?
Can stockholders call special meetings or act by consent?
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Next Prelude Therapeutics earnings date

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Q4 202513 Mar, 2026
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Frequently asked questions

Prelude Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on the development of novel, small molecule therapies targeting key drivers of cancer cell growth and resistance. Leveraging its expertise in cancer biology, medicinal chemistry, and drug development, Prelude Therapeutics is committed to advancing a pipeline of innovative treatments aimed at addressing the complex challenges of cancer treatment. The company is headquartered in Wilmington, Delaware, and its shares are listed on the Nasdaq.

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