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Rapport Therapeutics
Rapport Therapeutics (RAPP) investor relations material
Rapport Therapeutics 44th Annual J.P. Morgan Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.44th Annual J.P. Morgan Healthcare Conference summary14 Jan, 2026
Company vision and platform
Aims to be a leader in precision neuroscience, leveraging receptor-associated protein technology for targeted therapies.
Created through collaboration with Third Rock and J&J, bringing deep institutional knowledge.
Focuses on developing highly specific compounds for neurological conditions, improving efficacy and tolerability.
Lead program RAP-219 and clinical progress
RAP-219, a forebrain-restricted TARP gamma-8 AMPA modulator, showed robust phase 2 data in focal onset seizures.
Pivotal studies for RAP-219 to begin in Q2 2026, following positive FDA interaction.
Expanding indications to primary generalized tonic-clonic seizures and bipolar mania, with proof-of-concept data for bipolar expected in H1 2027.
Developing a long-acting injectable (LAI) formulation, with first human PK data expected in 2027.
Market opportunity and unmet needs
Focal onset seizures: 1.8M patients, $15B market; primary generalized tonic-clonic seizures: 800K patients, $7B market; bipolar mania: 1.5M patients, $40B market.
High unmet need due to limited efficacy and tolerability of current CNS drugs; RAP-219 aims to address these gaps.
LAI formulation expected to extend clinical utility and revenue durability.
Rationale for Alpha-6 pain program prioritization
RAP-219's competitive edge beyond efficacy?
LAI market penetration strategy and timing?
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Next Rapport Therapeutics earnings date
Q4 202511 Mar, 2026
Rapport Therapeutics
Next Rapport Therapeutics earnings date
Q4 202511 Mar, 2026
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Frequently asked questions
Rapport Therapeutics Inc. is a clinical-stage biopharmaceutical company dedicated to the discovery and development of small-molecule medicines targeting central nervous system disorders. The company's research focuses on understanding neuronal receptor biology to design precision treatments that address the complexities of neurological conditions. By mapping and targeting specific neuronal receptor complexes, Rapport aims to regulate receptor function and expression effectively. The company is headquartered in Boston, Massachusetts, and its shares are listed on NASDAQ.
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