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Rhythm Pharmaceuticals (RYTM) investor relations material
Rhythm Pharmaceuticals Corporate Presentation summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Strategic positioning and financial overview
IMCIVREE (setmelanotide) is available in over 25 countries, with a strong global commercial infrastructure and expanding indications for rare genetic obesity disorders.
Q4 2025 preliminary unaudited net revenues were approximately $57M, an 11% increase quarter-over-quarter, with FY 2025 revenues at ~$194M.
Cash, cash equivalents, and short-term investments totaled $416.1M as of September 30, 2025, sufficient to fund operations for at least 24 months.
Product pipeline and clinical development
Setmelanotide is advancing for acquired and congenital hypothalamic obesity, Prader-Willi syndrome, and additional rare MC4R pathway diseases.
Next-generation MC4R agonists, RM-718 (weekly injection) and oral bivamelagon, are in clinical development with patent protection into the 2040s.
Multiple clinical milestones are anticipated in 2026, including regulatory decisions, trial readouts, and pivotal trial initiations.
Market opportunity and patient impact
Significant market opportunities exist in acquired hypothalamic obesity (~10,000 US and EU prevalence each), Prader-Willi syndrome (~20,000 US, ~400,000 worldwide), and other rare genetic obesity disorders.
IMCIVREE is the first and only FDA- and EMA-approved therapy for early-onset, severe obesity and hyperphagia in Bardet-Biedl syndrome and certain genetic deficiencies.
Patient testimonials highlight transformative impacts on hunger and quality of life.
- TimeTickerHeadlineOpen
- 7 Feb514167
Quarterly and nine-month results reflect solid revenue, profit, and compliance with new labour codes. - 7 FebMGL
Strong revenue growth offset by lower margins and profit; interim dividend declared. - 7 FebPGIL
Strong revenue and margin growth, with India set for further expansion and upgraded ratings. - 7 Feb504614
Strong revenue and profit growth in Q3 FY26, led by power and steel segments. - 7 FebCHEMPLASTS
Net losses widened and revenue fell year-over-year amid regulatory and market headwinds. - 7 FebSBIN
Q3 FY26 net profit reached ₹21,028.15 crore, driven by robust income and strategic divestments. - 6 FebHTOO
Resale registration for 71,429 shares via warrant, with proceeds only on exercise; financial risks persist. - 6 FebVSAT
Q3 revenue up 3% to $1.16B, net income $25M, strong cash flow, Ligado boost, satellite focus. - 6 FebWEC
Targets 7–8% EPS growth, $37.5B capex, and coal exit by 2032 amid surging data center demand. - 6 FebBR
Q2 FY26 recurring revenue grew 8% and adjusted EPS guidance was raised to 9-12%.
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