SELLAS Life Sciences Group
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SELLAS Life Sciences Group (SLS) investor relations material

SELLAS Life Sciences Group Q4 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q4 2025 earnings summary19 Mar, 2026

Executive summary

  • Advanced pivotal Phase 3 REGAL trial of GPS in AML, with final analysis pending upon reaching 80 events.

  • First patient dosed in Phase 2 trial of SLS009 in newly diagnosed AML; positive Phase 2 data in relapsed/refractory AML presented at ASH 2025.

  • Entered European collaboration to expand SLS009 clinical program, with enrollment of 40 patients anticipated in Q2 2026.

Financial highlights

  • Cash and cash equivalents totaled $71.8 million as of December 31, 2025; an additional $42.6 million received in Q1 2026 from warrant exercises.

  • Research and development expenses were $16.0 million for 2025, down from $19.1 million in 2024.

  • General and administrative expenses were $12.3 million for 2025, slightly down from $12.4 million in 2024.

  • Net loss for 2025 was $26.9 million, or $0.25 per share, compared to $30.9 million, or $0.50 per share, in 2024.

  • Received $67.2 million in gross proceeds from warrant exercises in 2025.

Outlook and guidance

  • 2026 expected to be a pivotal year with REGAL trial final analysis and expansion of SLS009 into earlier AML treatment settings.

  • Additional clinical milestones anticipated, including European patient enrollment and further data disclosures.

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