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Seres Therapeutics (MCRB) investor relations material
Seres Therapeutics Piper Sandler 37th Annual Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Microbiome technology and therapeutic platform
Developed a platform to design bacterial consortia drugs targeting specific disease pathways, with two Breakthrough Therapy designations for VOWST and SER-155.
Manufacturing expertise includes cultivating novel bacteria, regulatory precedent with FDA, and advanced CMC processes for drug stability and cost efficiency.
SER-155 clinical development and unmet need
SER-155 targets infection, bacteremia, and graft-versus-host disease in allo-HSCT patients, addressing high infection rates and mortality.
Phase Ib data showed a 77% reduction in bloodstream infection risk, lower antibiotic use, and positive biomarker results.
FDA provided constructive feedback, agreeing on key phase II design elements, including endpoints, study size, and interim analysis.
Interim analysis may allow early pivotal study transition if efficacy is strong; safety profile in phase I was similar to placebo.
Commercial opportunity and pricing
Allo-HSCT market includes 40,000 annual transplants globally, concentrated in specialized centers for efficient outreach.
Protocol-driven care enables rapid adoption; strong value proposition due to high infection costs and outpatient reimbursement.
Comparable product PREVYMIS is priced at $25,000–$27,000 per course and has seen rapid uptake.
- TimeTickerHeadlineOpen
- 6 FebJ
Strong growth, digital innovation, and margin expansion drive robust multi-year financial outlook. - 6 Feb004020
Operating profit rose on cost savings and high-value sales, with major US expansion underway. - 6 FebJOUT
Net sales up 31%, gross margin at 36.6%, and net loss narrowed to $3.3 million. - 6 FebPECO
Record 2025 occupancy and 7% Core FFO growth; 2026 targets 5.5% FFO growth and strong acquisitions. - 6 FebPROV
Q2 FY2026 net income rose 65% year-over-year, with higher margins and strong credit quality. - 6 FebNVDA
AI-driven digital twins and accelerated computing are set to revolutionize industrial design and manufacturing. - 6 FebCDP
2025 FFO/share rose 5.8% to $2.72, with strong leasing and investment; 2026 guidance signals more growth. - 6 FebCRI
Q1 2025 saw record revenue, a return to profit, and major new contracts in space technology. - 6 FebCRI
Net loss widened to 7.5m PLN in H1 2024 as revenue fell and R&D costs remained high. - 6 FebCRI
Net loss deepened on lower sales and higher costs, but major new contracts and restructuring are underway.
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