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Sonnet BioTherapeutics Holdings (SONN) investor relations material
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Sonnet BioTherapeutics Holdings Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q4 2025 earnings summary16 Dec, 2025
Executive summary
Clinical-stage biotech focused on oncology, leveraging proprietary FHAB technology for targeted biologic medicines, with a pipeline led by SON-1010 (IL-12-FHAB) in solid tumors and SON-080 (IL-6) for neuropathy indications.
Completed a business combination with Hyperliquid Strategies Inc. and Rorschach I LLC in December 2025, becoming a wholly owned subsidiary of HSI.
Ongoing collaborations with Roche (atezolizumab combo) and Alkem (SON-080 in India); New Life Therapeutics partnership for SON-080 in ASEAN region is being renegotiated.
Financial highlights
Fiscal year ended September 30, 2025: Collaboration revenue of $1.0 million (Alkem Agreement), up from $18,626 in 2024.
Net loss of $16.0 million, compared to $7.4 million in the prior year, driven by increased R&D and G&A expenses.
Research and development expenses rose to $8.4 million (from $5.7 million), mainly due to higher clinical trial costs.
General and administrative expenses increased to $8.5 million (from $6.1 million), reflecting higher professional fees and transaction costs.
Cash and cash equivalents at year-end: $5.1 million; stockholders' equity: $10.8 million.
Cash used in operations: $12.8 million; net cash provided by financing activities: $26.0 million.
Outlook and guidance
Cash runway projected into February 2026; substantial additional financing required to fund operations and clinical development.
Focus on advancing SON-1010 in solid tumors and SON-080 in neuropathy, with ongoing cost management and prioritization of high-potential assets.
Plans to seek further equity, debt, or partnership funding; potential asset sales or operational reductions if capital is not secured.
Detail warrant proceeds spending restrictions
Explain HSI's business model impact on Sonnet funding
SON-080 development and partnering strategy update
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Frequently asked questions
Sonnet BioTherapeutics Holdings Inc is a U.S.-based clinical-stage biopharmaceutical company focused on the development of innovative biologic drugs for cancer and other serious diseases. The company utilizes a proprietary platform to design fully human fusion proteins that enhance the therapeutic activity and delivery of cytokines. Sonnet’s pipeline targets various solid tumors and immunological conditions, with development efforts supported by preclinical and clinical research. The company is headquartered in Princeton, New Jersey, and its shares are listed on the NASDAQ.
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