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TScan Therapeutics (TCRX) investor relations material
TScan Therapeutics KOL Event summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.KOL Event summary8 Dec, 2025
Introduction and agenda
Presented updated data from the ALLOHA phase I study and discussed the market opportunity for TSC-101, a next-generation TCR-T cell therapy for hematologic malignancies.
Outlined plans to launch a pivotal study of TSC-101 in Q2 2026 and provided updates on manufacturing and regulatory progress.
Virtual KOL event scheduled for December 8 to discuss updated ALLOHA Phase 1 trial data, manufacturing improvements, and market opportunity for TSC-101 and future candidates.
KOL background and credentials
Dr. Ran Reshef, Director of Translational Research and Blood and Marrow Transplantation at Columbia University, presented updated clinical data.
Presenters included Gavin MacBeath, Ph.D., Stephen Camiolo, BSN, ACNP, and Chrystal Louis, M.D., M.P.H., each contributing expertise in clinical, manufacturing, and market aspects.
Market insights and analysis
TSC-101 targets HLA-A*02:01 positive patients, representing about 2,100 addressable U.S. patients at launch and a $1.4B+ peak revenue opportunity.
Expansion to additional HLA types (TSC-102) could double the global addressable market to 15,000–20,000 patients.
Allogeneic HCT is the only curative option for AML/MDS, but 38-44% relapse within two years, highlighting a significant unmet need.
The treatment landscape is highly concentrated, with 40 centers expected to treat two-thirds of eligible U.S. patients.
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Next TScan Therapeutics earnings date
Q4 20255 Mar, 2026
Next TScan Therapeutics earnings date
Q4 20255 Mar, 2026
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Frequently asked questions
TScan Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing T cell receptor-engineered T cell (TCR-T) therapies to treat cancer. The company's lead candidates, TSC-100 and TSC-101, target hematologic malignancies like acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) to eliminate residual disease and prevent relapse following allogeneic hematopoietic cell transplantation. Additionally, TScan is advancing a pipeline of multiplexed TCR-T therapies for solid tumors, supported by its proprietary ImmunoBank, which houses a diverse collection of therapeutic TCRs. The company is headquartered in Waltham, Massachusetts, and its shares are listed on the NASDAQ.
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