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Vanda Pharmaceuticals (VNDA) investor relations material
Vanda Pharmaceuticals Q1 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Q1 2026 net product sales reached $51.7 million, up 3% year-over-year, driven by 26% FanaptⓇ sales growth and the launch of NEREUS™, while BYSANTI™ received FDA approval for bipolar I disorder and schizophrenia with exclusivity through 2031 and patents to 2044.
NEREUS™ launched as the first new prescription therapy for motion sickness prevention in over 40 years, leveraging a direct-to-consumer platform.
Net loss widened to $48.6 million (diluted loss per share of $0.82) from $29.5 million (diluted loss per share of $0.50) in Q1 2025, reflecting higher SG&A and milestone payments.
Late-stage clinical pipeline progressing, with multiple Phase III readouts for BYSANTI™, NEREUS™, and VQW-765 expected in 2026–2027.
Financial highlights
Q1 2026 revenues were $51.7 million, a 3% increase year-over-year, with FanaptⓇ net sales at $29.6 million (+26%), HETLIOZⓇ at $15.9 million (-24%), and PONVORYⓇ at $6.2 million (+10%).
Operating expenses increased to $101.9 million, mainly due to higher SG&A and launch preparations.
Cash, cash equivalents, and marketable securities were $202.3 million as of March 31, 2026, down $61.5 million from year-end 2025, including a $10 million milestone payment to Eli Lilly for NEREUS™ approval.
Cost of goods sold was $3.2 million, representing 6% of revenue; R&D expenses dropped to $28.4 million.
Net cash used in operating activities was $50.2 million for Q1 2026, up from $33.1 million in Q1 2025.
Outlook and guidance
Full-year 2026 revenue guidance raised to $240–$290 million, with FanaptⓇ expected to contribute $150–$170 million and NEREUS™ $10–$30 million.
Guidance assumes further HETLIOZⓇ decline and modest PONVORYⓇ growth; NEREUS™ guidance based on market modeling, not actual sales data.
2026 cash burn expected to exceed 2025 levels; significant working capital needs anticipated through 2026 and beyond.
Cash and equivalents projected to be sufficient for at least the next 12 months.
- Proxy covers director elections, compensation, auditor ratification, and equity plan amendment.VNDA
Proxy filing23 Apr 2026 - Key votes include director elections, auditor ratification, and equity plan amendment.VNDA
Proxy filing23 Apr 2026 - BYSANTI and Nereus launches in 2026 drive growth amid expanding late-stage pipeline.VNDA
The Citizens Life Sciences Conference 20261 Apr 2026 - Poised for major 2026 growth with new approvals, strong pipeline, and rising prescription demand.VNDA
Corporate presentation11 Mar 2026 - Shelf registration allows up to $200M in securities for growth and R&D in specialty pharma.VNDA
Registration Filing12 Feb 2026 - 2025 revenues rose 9% to $216.1M, led by Fanapt and Nereus approval; 2026 guidance is $230–$260M.VNDA
Q4 202511 Feb 2026 - Q2 2024 revenue up 10% to $50.5M, but net loss widened on higher SG&A and lower HETLIOZ sales.VNDA
Q2 20242 Feb 2026 - Expanding indications and new launches drive growth, supported by strong cash reserves.VNDA
Jefferies 2024 Global Healthcare Conference1 Feb 2026 - Product launches, pipeline progress, and strong cash position drive growth outlook.VNDA
2024 Wells Fargo Healthcare Conference21 Jan 2026
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