Vanda Pharmaceuticals
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Vanda Pharmaceuticals (VNDA) investor relations material

Vanda Pharmaceuticals Q1 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q1 2026 earnings summary6 May, 2026

Executive summary

  • Q1 2026 net product sales reached $51.7 million, up 3% year-over-year, driven by 26% FanaptⓇ sales growth and the launch of NEREUS™, while BYSANTI™ received FDA approval for bipolar I disorder and schizophrenia with exclusivity through 2031 and patents to 2044.

  • NEREUS™ launched as the first new prescription therapy for motion sickness prevention in over 40 years, leveraging a direct-to-consumer platform.

  • Net loss widened to $48.6 million (diluted loss per share of $0.82) from $29.5 million (diluted loss per share of $0.50) in Q1 2025, reflecting higher SG&A and milestone payments.

  • Late-stage clinical pipeline progressing, with multiple Phase III readouts for BYSANTI™, NEREUS™, and VQW-765 expected in 2026–2027.

Financial highlights

  • Q1 2026 revenues were $51.7 million, a 3% increase year-over-year, with FanaptⓇ net sales at $29.6 million (+26%), HETLIOZⓇ at $15.9 million (-24%), and PONVORYⓇ at $6.2 million (+10%).

  • Operating expenses increased to $101.9 million, mainly due to higher SG&A and launch preparations.

  • Cash, cash equivalents, and marketable securities were $202.3 million as of March 31, 2026, down $61.5 million from year-end 2025, including a $10 million milestone payment to Eli Lilly for NEREUS™ approval.

  • Cost of goods sold was $3.2 million, representing 6% of revenue; R&D expenses dropped to $28.4 million.

  • Net cash used in operating activities was $50.2 million for Q1 2026, up from $33.1 million in Q1 2025.

Outlook and guidance

  • Full-year 2026 revenue guidance raised to $240–$290 million, with FanaptⓇ expected to contribute $150–$170 million and NEREUS™ $10–$30 million.

  • Guidance assumes further HETLIOZⓇ decline and modest PONVORYⓇ growth; NEREUS™ guidance based on market modeling, not actual sales data.

  • 2026 cash burn expected to exceed 2025 levels; significant working capital needs anticipated through 2026 and beyond.

  • Cash and equivalents projected to be sufficient for at least the next 12 months.

BYSANTI switch strategy ahead of Fanapt LOE
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H.C. Wainwright 4th Annual BioConnect Investor Conference19 May, 2026
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H.C. Wainwright 4th Annual BioConnect Investor Conference19 May, 2026

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