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10X Genomics (TXG) Q1 2026 earnings summary

Event summary combining transcript, slides, and related documents.

Logotype for 10X Genomics Inc

Q1 2026 earnings summary

7 May, 2026

Executive summary

  • Achieved $150.8 million in Q1 2026 revenue, up 9% year-over-year excluding prior year settlement/license revenue.

  • Launched Atera, a major new spatial biology platform, with strong early demand, pre-orders, and shipments expected in H2 2026.

  • Double-digit growth in both single-cell and spatial consumables, driven by Flex Apex and Xenium.

  • Maintained disciplined cost management, with operating expenses down 15–20% year-over-year excluding one-time items.

  • Announced partnerships and initiatives in AI-driven biology and translational research, including Bioptimus and STELA.

Financial highlights

  • Q1 2026 revenue: $150.8 million, up 9% year-over-year excluding non-recurring settlement/license revenue.

  • Consumables revenue up 13%; single-cell consumables up 6%, spatial consumables up 31%.

  • Instrument revenue declined 24% year-over-year; Chromium instruments down 12%, spatial instruments down 32%.

  • Gross margin improved to 70% from 68% in Q1 2025, driven by lower warranty and inventory costs.

  • Ended quarter with $540 million in cash and equivalents, up $113 million year-over-year.

Outlook and guidance

  • Full-year 2026 revenue expected at $600–$625 million, representing 0–4% growth over 2025 excluding settlement/license revenue.

  • Double-digit growth anticipated in single-cell and spatial consumables for the year.

  • Q2 and Q3 revenue expected to decline sequentially due to customers delaying spatial purchases ahead of Atera launch.

  • Atera shipments to begin contributing in Q4/H2, with initial production capacity limited.

  • Gross margin for 2026 expected in the mid-60s%, with some pressure from Atera launch in Q4.

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