Shattuck Labs (STTK) Registration Filing summary
Event summary combining transcript, slides, and related documents.
Registration Filing summary
13 Jan, 2026Company overview and business model
Specializes in developing treatments for inflammatory and immune-mediated diseases, with a focus on a first-in-class antibody for inflammatory bowel disease and related conditions.
Lead program, SL-325, is a death receptor 3 antagonist antibody, leveraging expertise in protein engineering and TNF receptor therapeutics.
Incorporated in Delaware in 2016, with principal offices in Austin, TX.
Risk factors and disclosures
Faces risks related to clinical trial timing, patient enrollment, R&D costs, regulatory approvals, and commercialization.
Exposed to market, competitive, and macroeconomic risks, including inflation, economic downturns, and public health crises.
Risks and uncertainties are detailed in incorporated SEC filings, including annual and quarterly reports.
Use of proceeds and capital allocation
Net proceeds will be used to advance clinical trials, develop additional product candidates, and for working capital and general corporate purposes.
May allocate funds to license, acquire, or invest in complementary businesses or technologies, though no current commitments exist.
Pending use, proceeds may be invested in capital preservation instruments.
Latest events from Shattuck Labs
- SL-325 offers a novel, potent approach to IBD by targeting DR3, with Phase 2 trials planned.STTK
Corporate presentation5 Mar 2026 - SL-325 clinical progress and a strengthened cash position extend operational runway into 2029.STTK
Q4 20255 Mar 2026 - DR3 antibody program targets superior efficacy and lower immunogenicity in IBD, with phase IIb trial soon.STTK
TD Cowen 46th Annual Health Care Conference2 Mar 2026 - SL325, a DR3-targeting antibody, advances to clinical trials for IBD with IND planned mid-2025.STTK
Piper Sandler 36th Annual Healthcare Conference3 Feb 2026 - SL-172154 plus azacitidine achieved high response rates and manageable safety in HR-MDS and TP53 mutant AML.STTK
Study Update3 Feb 2026 - SL-172154 discontinued for marginal benefit; SL-325 DR3 antibody advances to phase I in 2026.STTK
Study Update20 Jan 2026 - DR3 targeting may deliver more durable and effective IBD therapy, with clinical data expected in 2026.STTK
7th Annual Evercore ISI HealthCONx Healthcare Conference12 Jan 2026 - SL-325, a first-in-class DR3 antibody, enters clinical trials in 2024 to advance IBD treatment.STTK
43rd Annual J.P. Morgan Healthcare Conference 202510 Jan 2026 - Over 105 million shares registered for resale; proceeds from warrants fund clinical development.STTK
Registration Filing16 Dec 2025