Achieved $599 million in 2025 revenue and $166 million in Q4, surpassing guidance, with year-end cash balance exceeding $520 million and over $100 million cash growth from 2024.
Q4 growth was driven by both instruments and consumables, with CapEx growing nearly 30% sequentially and Chromium consumables reactions up more than 20%.
Chromium instrument placements reached over 6,400 cumulatively, with 1,500 spatial instruments sold by end of 2025; instrument demand remains challenged by tight capital budgets.
Spatial consumables and the Flex assay saw strong momentum, with Flex becoming the most popular assay by volume last quarter.
Plan to reinstate full-year guidance during the Q4 call, barring unforeseen circumstances.
Operates three category-defining platforms, launching over 35 major products in the last decade and maintaining the largest ecosystem of users and publications.
Chromium leads in single cell analysis, with Flex assay offering sensitivity, flexibility, and cost-effectiveness.
Spatial platforms Visium and Xenium enable comprehensive molecular, cellular, and tissue analysis; Xenium is now the primary growth engine in spatial.
Multi-omics capabilities introduced with Xenium RNA and protein panel, receiving strong initial feedback for practical, scalable workflows.
Acquired Scale Biosciences to enhance experiment scale and integrate new technologies into the Chromium portfolio.
Integrates large-scale biological data with AI models to accelerate understanding and medicine development.
Supports development of virtual cell foundation models, collaborating with leading academic and industry partners.
Provides massive, high-quality datasets essential for training AI models in therapeutic discovery.
Announced partnership with Cancer Research Institute to build a Discovery Engine dataset for immunotherapy and a high-resolution immune atlas.
AI partnerships, such as with Anthropic, aim to address data analysis bottlenecks and further integrate AI into research workflows.
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