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Indivior Piper Sandler 37th Annual Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Piper Sandler 37th Annual Healthcare Conference summary2 Dec, 2025
Strategic vision and organizational changes
Launched a three-phased, multi-year operational roadmap (Indivior Action Agenda) to maximize business value and shareholder returns.
Aims to become a leading diversified specialty pharmaceutical company focused on differentiated medicines.
Simplified the organization by removing nonessential activities and costs, reducing OPEX by $150 million.
OPEX will not exceed $450 million by 2026, with significant cuts in G&A and right-sizing R&D and medical affairs.
Scaled back international presence from 41 to 4 countries, focusing on Canada, Australia, France, and Germany.
R&D and portfolio management
Phase 2 programs (Indivior 6001 and 2000) fully funded, with data readouts expected in early Q2 2026.
Future R&D spend will be disciplined, advancing only programs deemed worthy.
Commercial support for OPVEE discontinued due to lack of synergy and market viability.
OPVEE was supported by a separate infrastructure and faced market challenges like high costs and generic competition.
Financial outlook and profitability
Remaining in four international markets retains 77% of forecasted net revenue and 94% of EBITDA.
Exiting unprofitable or subscale markets; overall profitability impact is immaterial.
Significant margin improvement expected by 2026, with detailed guidance to be issued before JP Morgan conference.
R&D strategy beyond current pipeline
DTC investment: Expected LAI penetration impact?
M&A criteria for non-addiction assets?
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Q4 202519 Feb, 2026
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Frequently asked questions
Indivior PLC is a pharmaceutical company focused on developing treatments for substance use disorders and mental health conditions. The company's core business revolves around the research, development, and commercialization of therapies aimed at addressing opioid dependence, alcohol use disorder, and other addiction-related conditions. Indivior also provides products in the area of behavioral health, contributing to the treatment of mental health conditions. Its portfolio includes both oral and injectable treatment options, designed to support patients in managing chronic conditions related to substance dependence. The company is headquartered in North Chesterfield, Virginia, and its shares are listed on the London Stock Exchange.
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